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Sitagliptin is prescribed for individuals with type 2 diabetes to help manage high blood sugar levels. It is most effective when used alongside a healthy diet, regular exercise, and sometimes in combination with other medications. By maintaining proper blood sugar control, sitagliptin aids in preventing complications like kidney damage, vision loss, nerve issues, amputations, and sexual dysfunction. Additionally, it may reduce the risk of heart attack or stroke. Sitagliptin functions by boosting the levels of incretins, natural substances that enhance insulin release following meals and reduce sugar production in the liver.